Assay Development

The overarching goal for Assay Development focuses on the timely delivery of robust and well validated assays to uHTS.  Over the last 12 months, the Assay Development group has worked on more than 50 assays from 29 PI’s outside of the MLSCN Center of which 13 were also outside of the Scripps Research Institute. 23 assays were successfully transferred to uHTS.  The breadth of our assay development production competency and the extent of our Outreach efforts to other institutions on behalf of MLSCN is demonstrated by the range of target classes and assay platforms shown below:

Assay Formats

Screening Capabilities

Biologicial Expertise

  • Fluorescence Intensity
  • Fluorescence Polarization
  • TRF
  • FRET
  • Luminescence
  • Absorbance
  • AlphaScreen
  • FITC
  • GFP
  • Cell Imaging
  • Fluorescent Microscopy
  • GPCRs
  • Receptor-ligand interaction
  • Protein-protein interactions
  • Enzyme Assays
  • Ion Channels
  • Reporter Assays
  • Viability Assays
  • Protein Translocation

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